| Preseptal Cellulitis  SIGNS AND SYMPTOMS
Patients with preseptal cellulitis will present with an acutely painful,
swollen eyelid. Because of the pronounced edema, the patient may not be able to open his
or her eyes. However, there will be no disturbance in visual acuity or ocular motility,
nor any signs of proptosis. There may be a concurrent history of sinus infection or
congestion, penetrating trauma to the eyelid, or dental infection. In most cases, the
patient will be systemically well and afebrile (not feverish).
PATHOPHYSIOLOGY
The eyelid is separated into preseptal and postseptal areas by the orbital
septum, which prevents the spread of infection to the orbit and central nervous system.
Preseptal cellulitis is a bacterial infection of the eyelid anterior to the orbital
septum. The routes of infection include direct inoculation from trauma, or spread of
infection from the neighboring ethmoid sinus or teeth.
The most commonly encountered organisms include Staphylococcus aureus,
Streptococcus pyogenes and Streptococcus pneumoniae. If a human or animal bite wound is
the source, suspect anaerobic bacteria such as Peptostreptococcus and Bacteroides. If the
infection spreads posterior to the orbital septum, it may result in a postseptal (or
orbital) cellulitis, with associated vision loss, ocular motility restrictions and
proptosis. Patients with orbital cellulitis are systemically ill and febrile.
MANAGEMENT
To prevent the possibly disastrous spread of infection to the postseptal
area, it is crucial to quickly suppress the infection. Oral therapy is necessary; topical
antibiotics alone are insufficient. Amoxicillin 500mg PO TID is an excellent choice,
although you may substitute nafacillin, oxacillin or cefazolin. If the cause is a bite
wound, consider ampicillin or clindamycin. In cases of concurrent sinus infection, you may
wish to consult an otolaryngologist to help you identify the involved organism.
CLINICAL PEARLS
Often, insect bites can mimic preseptal cellulitis, but these are
rarely infectious. Instead, the patient will have a severe local allergic reaction. If the
lid is not extremely painful upon palpation, it is usually an insect bite. A short course
of oral antihistamines or steroids and cold compresses will often be sufficient. If you
are in doubt as to the infectious nature of an insect bite, proceed with oral antibiotic
therapy as well.
Lacrimal gland inflammation (dacryoadenitis) can also mimic preseptal
cellulitis. Though rare, it usually occurs in adolescent viral infections such as mumps,
influenza and measles.
Other reports in this section
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